Abstract: The medicated chewing gum containing methyl prednisolone IP may be an excellent formulation to treat oral ulcer caused by the consumption of. An attempt has been made to formulate new chewing gum device for metaclopramide in the form of tablet. The new drug delivery system was obtained , at room. Formulation and evaluation of medicated chewing gum as antiplaque and antibacterial agent. S Vasudha Lakshmi1, Hemant KS Yadav1*, KP Mahesh2, Swati.
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FORMULATION AND EVALUATION OF MEDICATED CHEWING GUM OF DOLASETRON AS AN ANTIEMETIC AGENT
Journal of Current Pharma Research ; 4 4: Announcements Editorial Board Indexing Contact. The volunteers were visually examined for presence or absence of gingival erythema, gingival edema and gingival bleeding and the antibacterial activity was assessed by the reduction in bacterial count in the plaque samples.
Open Access Pharmaceutics Research Journal. Hot melt technique was used to prepare chewing gums. Simple diffusion into the medium causes the release of only a small percentage of the drug contained in the medicated chewing gum, while the delivery of the major part of the dose occurs during mastication.
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The new drug delivery system was obtained, at room temperature conventional pharmaceutical equipment. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 3.
Pharmaceutica Analytica Acta Open Access. Urinary excretion profile showed that within the short span of time 1. Hence, Metaclopramide chewing gum can be considered as a better formulation for the buccal drug delivery system, in formularion drug is absorbed buccally and reaches the systemic circulation via jugular vein.
An attempt has been made to formulate new chewing gum for Dolasetron.
Abstract An attempt has been made to formulate new chewing gum for Dolasetron. Evaluatoon new drug delivery system was obtained, at room temperature, by direct compression using conventional pharmaceutical equipment. Simple diffusion into the medium causes the release of only a small percentage of the drug contained in the medicated chewing gum, while the delivery of the major part of the dose occurs during mastication.
Formulation And Evaluation Of Medicated Chewing Gum Of Metaclopramide |
In the present study, an attempt has been made to formulate the chewing gum of Dolasetron. The resulting chewing gum comprises a gum core combined with fillers, antioxidants, coloring agent evzluation plasticizers, which provide smooth appearance and flexibility during storage and chewing.
The dose of chlorhexidine can be reduced significantly when used along with chitosan. The prepared gums were evaluated for physical parameters, compatibility studies, drug content, moisture content, stability studies and in vitro drug-release testing. Naik H, Gupta S.
The test group administered chewing gums containing chlorhexidine, with and without the polymer, while the control group administered dummy chewing gums. Paresh is having 3 International review articles and He is attended 1 National conferences in Solan H. Chewing gum, chitosan, chlorhexidine, dental caries. Vol 7 No 4 From this study, we can conclude that the medicated chewing formulation can be a better choice in the coming years which provides several benefits and also benefits commercially.
Paresh Mohan completed B. Guidelines Upcoming Special Issues. Ezhumlai K, Rajalakshmi A. Volume 7, Issue 4, July-August Madan N, Rathnam A. The 5- Hydroxytrytryptamin Receptor Antagonist as Antiementis: The aim of this study was to formulate chewing gum using chlorhexidine and chitosan and to prove its antibacterial and antiplaque properties effectively at low doses of chlorhexidine.
Analysis of variance revealed significant differences between subjects receiving F1 and F5 for antiplaque activity. Authors who publish with this journal agree to the following terms: Presently he is an M. The formulation, which contains highest concentration of chitosan, showed more in vitro chewin compared to other formulation. Chitosan containing chewing gum has a greater antibacterial effect compared with gums containing only chlorhexidine.
The resulting chewing gum tablets comprise a gum core combined with fillers, antioxidants, coloring agent and plasticizers, which provide smooth appearance and flexibility during fromulation and chewing.